HELLO, I'M
Abdul Bari Shah
Research Professor
About
Dr. Abdul Bari Shah
College of Pharmacy, Korea University, Sejong 30019, Republic of Korea
As a researcher Professor at the College of Pharmacy, Korea University, I am passionate about discovering new bioactive small molecules from bacteria, plants and fungi and developing dereplication by establishing a spectral big database of natural compounds. Currently involves in the isolation of bioactive compounds from natural sources, molecular networking, molecular simulations, and various biological activities, including enzyme kinetics, antiallergic studies, online assays, and more. Browse my site to learn more about my work.
Education
MY BACKGROUND
Experience
WHERE I'VE WORKED
2020-2023
Gyeongsang National University, Jinju, South Korea; PhD in Natural Products Chemistry
2024-present
College of Pharmacy, Korea University, Sejong 30019, Republic of Korea
2018-2020
Gyeongsang National University, Jinju, South Korea; Master in Natural Products Chemistry
2012-2016
University of Malakand, Department of Chemistry, Pakistan, BS(Hons), Chemistry
2023-2024
Natural Products Research Institute, College of Pharmacy, Seoul National University, South Korea. Postdoctoral Researcher
2017-2018
University of Malakand, Department of Chemistry, Pakistan. Research Assistant
Skills
WHAT I BRING TO THE TABLE
Natural Products Chemistry (Plants, Bacteria and Fungi
Spectroscopy
Bioassays
Data Analysis
LCMS
Research Writing
Presentation
English
Urdu
Pashto
Current Research Work
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Shah, A. B.; Park, Y.S.; Shim, S.H. Immunomodulatory and Anti-inflammatory Potentials of New Lipopeptides from Probiotic Bacillus velezensis (In submission to Food Chemistry)
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Shah, A. B.; Shim, S.H. Human Microbiota Peptides: Important Roles in Human Health Issues (Synopsis accepted in Natural Product Reports, under review, https://www.rsc.org/npr/)
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Shah, A. B.; Baiseitova, A.; Probiotic Significance of Lactobacillus Strains: A Comprehensive Review on Health Impacts, Research Gaps, and Future Prospects (Under Review as a corresponding author, Gut Microbes, https://www.tandfonline.com/journals/kgmi20)
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Shah, A. B.; Baiseitova, A.; Ugonins from Helminthostachys Zeylanica, Biological Properties and Future Direction: A Review (Under Review as a corresponding author, Phytochemistry Review, https://link.springer.com/journal/11101)
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Shah, A. B.; Khan. S.; Baiseitova, A.; Park, K. H. Dihydrobenzoxanthones activated insulin pathway by inhibition PTP1B and DPP4: Enzyme kinetics, cell based and Molecular simulation studies (submitted soon to International Journal of Biological Macromolecules, https://www.sciencedirect.com/journal/international-journal-of-biological-macromolecules)
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Shah, A. B.; Baiseitova, A.; Endophytes as a source of Antioxidant and Antiaging Agents. Invited Book Chapter for Taylor and Francis. (With Book editor)
Publications
MY RESEARCH WORKS
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Shah, A. B.; Baiseitova, A.; Lee. G, Kim, J. H.; Park, K. H. Investigation of Responsible Phenolic Metabolites for PTP1B Inhibition from Artocarpus elasticus. ACS Omega, 2024, 9, 8, 9053–9062. https://doi.org/10.1021/acsomega.3c07471.
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Baiseitova, A*.; Shah, A. B*.; Idress, M.; Kong, L.K.; Park, K. H. Antioxidant potentials of furanodihydrobenzoxanthones from Artocarpus elasticus and their protection against oxLDL induced injury in SH-SY5Y cells. Biomedicine & Pharmacotherapy, 2023,165, 115278. https://doi.org/10.1016/j.biopha.2023.115278.
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Shah, A. B.; Baiseitova, A.; Kim, J. H.; Lee, Y. H.; Park, K. H. Inhibition of Bacterial Neuraminidase and Biofilm Formation by Ugonins Isolated from Helminthostachys Zeylanica (L.) Hook. Frontiers in Pharmacology, 2022, 13, 10. https://doi.org/10.3389/fphar.2022.890649.
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Shah, A. B.; Yoon, S.; Kim, J. H.; Zhumanova, K.; Ban, Y. J.; Lee, K. W.; Park, K. H. Effectiveness of Cyclohexyl Functionality in Ugonins from Helminthostachys Zeylanica to PTP1B and α-Glucosidase Inhibitions. International Journal of Biological Macromolecules, 2020, 165, 1822–1831. https://doi.org/10.1016/j.ijbiomac.2020.10.061.
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Rehman F.; Shah, A. B*.; Muhammad. M.; Khan. E.; Ataya. F. S.; Batiha. G.E. Antioxidant, antibacterial, enzyme inhibition and fluorescence characteristics of unsymmetrical thiourea derivatives. Heliyon, 2024, 10, e31563. https://doi.org/10.1016/j.heliyon.2024.e31563.
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Lee, Y. H.; Kim, J. H.: Baiseitova, A.; Shah, A. B.; Im, S.Y.; Kim. J.Y.; Lee, Y.B.; Park, K. H. Selective induction of furanocoumarins in Angelica acutiloba roots by signaling molecule, ethylene and their monoamine oxidase inhibition. Industrial Crops and Products, 2024, 213, 118418. https://doi.org/10.1016/j.indcrop.2024.118418.
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Khan, S.; Ullah, I.; Rahman, M.U.; Khan, H.; Shah, A. B.; Althomali, R.H.; Rahman, M.M. Inorganic-polymer composite electrolytes: basics, fabrications, challenges and future perspectives. Reviews in Inorganic Chemistry, 2024, https://doi.org/10.1515/revic-2023-0030.
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Lee, Y. H.; Wang. Y.; Kim. J.Y.; Lee, G.H.; Kim, J. H.; Shah, A. B.; Park, K. H. Enzymatic evaluation of chromenone derivatives from Flemingia philippinensis as viral neuraminidase (H3N2) inhibitors. Journal of Molecular Structure, 2023, 1293, 136243. https://doi.org/10.1016/j.molstruc.2023.136243.
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Bibi, C.; Hadi, F.; Ali, N.; Zahoor, M.; Zeb, M.; Ullah, R.; Ali, E.A.; Shah, A.B. Cold-acclimation effect on cadmium absorption and biosynthesis of polyphenolics, and free proline and photosynthetic pigments in Spirogyra aequinoctialis. Open Chemistry, 2023, 21: 20230127. https://doi.org/10.1515/chem-2023-0127.
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Khan, S.; Rahman, F. U.; Zahoor, M.; Haq, A.U.; Shah, A. B.; Rahman, M.U.; Rahman, H.U. The DNA threat probing of some chromophores using UV/VIS spectroscopy. World Journal of Biology and Biotechnology, 2023. 8, 2. https://doi.org/10.33865/wjb.008.02.0962.
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Kim. J.Y.; Lee, Z. P.; Lee, G.H.; Kim, J. H.; Shah, A. B.; Lee, Y. H.; Park, K. H. Investigation of bacterial neuraminidase inhibition of xanthones bearing geranyl and prenyl groups from Cratoxylum cochinchinense. Frontiers in Chemistry, 2023, 11. https://doi.org/10.3389/fchem.2023.1245071.
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Kim, J. H.; Jeong, Y. J.; Lee, Y. H, Shah, A.B.; Kim, C.H.; Park, K. H. 1-Aminocyclopropane-1-carboxylic Acid Enhances Phytoestrogen Accumulation in Soy Plants (Glycine max L.) by Its Acceleration of the Isoflavone Biosynthetic Pathway. Journal of Agricultural and Food Chemistry, 2023, 71, 10393−10402. https://doi.org/10.1021/acs.jafc.3c01810.
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Ullah, Z.; Islam, N.; Ikram, M.; Zahoor, M.; Nazir, M.; Naz, S.; Ullah, R.; Bari, A.; Shah, A.B. Heavy metal transportation from polluted water into human through fodder plants and farmed animals. Zeitschrift für Physikalische Chemie, 2023, 0 (0). https://doi.org/10.1515/zpch-2023-0212.
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Ikram, M.; Zahoor, M.; Naeem, M.; Islam, N. U.; Shah, A. B.; Shahzad, B. Bacterial Oxidoreductive Enzymes as Molecular Weapons for the Degradation and Metabolism of the Toxic Azo Dyes in Wastewater: A Review. Zeitschrift für Physikalische Chemie, 2022, 0 (0). https://doi.org/10.1515/zpch-2022-0150.
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Khan, Q.; Zahoor, M.; Salman, S. M.; Wahab, M.; Talha, M.; Kamran, A. W.; Khan, Y.; Ullah, R.; Ali, E. A.; Shah, A. B. The Chemically Modified Leaves of Pteris Vittata as Efficient Adsorbent for Zinc (II) Removal from Aqueous Solution. Water, 2022, 14 (24), 4039. https://doi.org/10.3390/w14244039.
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Baiseitova, A.; Lee, G.; Shah, A. B.; Yoon, S.; Kim, J. H.; Lee, Y. H.; Park, K. H. New Dihydrobenzoxanthone Derivatives with Bacterial Neuraminidase Inhibitory Activity Isolated from Artocarpus Elasticus. Bioorganic Chemistry, 2022, 127, 105978. https://doi.org/10.1016/j.bioorg.2022.105978.
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Kim, J. H.; Shah, A. B.; Lee, Y. H.; Baiseitova, A.; Ban, Y. J.; Park, K. H. Changes in Secondary Metabolites in Soybean (Glycine Max L.) Roots by Salicylic Acid Treatment and Their Anti-LDL Oxidation Effects. Frontier Plant Science, 2022, 13, 1000705. https://doi.org/10.3389/fpls.2022.1000705.
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Ikram, M.; Naeem, M.; Zahoor, M.; Rahim, A.; Hanafiah, M. M.; Oyekanmi, A. A.; Shah, A. B.; Mahnashi, M. H.; Al Ali, A.; Jalal, N. A.; Bantun, F.; Sadiq, A. Biodegradation of Azo Dye Methyl Red by Pseudomonas Aeruginosa: Optimization of Process Conditions. International Journal of Environmental Research and Public Health, 2022, 19 (16), 9962. https://doi.org/10.3390/ijerph19169962.
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Khan, A. U.; Zahoor, M.; Rehman, M. U.; Shah, A. B.; Zekker, I.; Khan, F. A.; Ullah, R.; Albadrani, G. M.; Bayram, R.; Mohamed, H. R. H. Biological Mineralization of Methyl Orange by Pseudomonas Aeruginosa. Water, 2022, 14 (10), 1551. https://doi.org/10.3390/w14101551.
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Latif, M.; Zahoor, M.; Muhammad, A.; Naz, S.; Kamran, A. W.; Ullah, R.; Shah, A. B.; Almeer, R.; Sayed, A. Bioaccumulation of Lead in Different Organs of Ctenopharyngodon Idella (Grass Fish) and Tor Putitora (Mahseer) Fish. Brazilian Journal of Biology, 2024, 84, e260355. https://doi.org/10.1590/1519-6984.260355.
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Baiseitova, A.; Ban, Y. J.; Kim, J. Y.; Lee, G.; Shah, A. B.; Kim, J. H.; Lee, Y. H.; Park, K. H. Soybean Phytochemicals Responsible for Bacterial Neuraminidase Inhibition and Their Characterization by UPLC-ESI-TOF/MS. Food & Function, 2022, 13 (13), 6923–6933. https://doi.org/10.1039/D2FO00537A.
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Khan, A. U.; Rehman, M. U.; Zahoor, M.; Shah, A. B.; Zekker, I. Biodegradation of Brown 706 Dye by Bacterial Strain Pseudomonas Aeruginosa. Water, 2021, 13 (21), 2959. https://doi.org/10.3390/w13212959.
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Baiseitova, A.; Shah, A. B.; Kim, J. Y.; Ban, Y. J.; Kim, J. H.; Nafiah, M. A.; Park, K. H. O-Alkylated Quercetins with Selective Acetylcholinesterase and β-Secretase Inhibitions from Melicope Glabra Leaves, and Their Flavonols Profile by LC-ESI-Q-TOF/MS. Journal of Functional Foods, 2021, 84, 104602. https://doi.org/10.1016/j.jff.2021.104602.
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Ihsan, M.; Nazir, N.; Ghafoor, A.; Khalil, A.; Zahoor, M.; Nisar, M.; Khames, A.; Ullah, R.; Shah, A.B. Genetic Diversity in Local and Exotic Avena Sativa L. (Oat) Germplasm Using Multivariate Analysis. Agronomy, 2021, 11 (9), 1713. https://doi.org/10.3390/agronomy11091713.
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Khan, J.; Majid, A.; Nazir, N.; Nisar, M.; Khan Khalil, A. A.; Zahoor, M.; Ihsan, M.; Ullah, R.; Bari, A.; Shah, A. B. HPLC Characterization of Phytochemicals and Antioxidant Potential of Alnus Nitida (Spach) Endl. Horticulturae, 2021, 7 (8), 232. https://doi.org/10.3390/horticulturae7080232.
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Rahman, F. U.; Bibi, M.; Khan, E.; Shah, A. B.; Muhammad, M.; Tahir, M. N.; Shahzad, A.; Ullah, F.; Zahoor, M.; Alamery, S.; Batiha, G. E.-S. Thiourea Derivatives, Simple in Structure but Efficient Enzyme Inhibitors and Mercury Sensors. Molecules, 2021, 26 (15), 4506. https://doi.org/10.3390/molecules26154506.
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Zhumanova, K.; Lee, G.; Baiseitova, A.; Shah, A. B.; Kim, J. H.; Kim, J. Y.; Lee, K. W.; Park, K. H. Inhibitory Mechanism of O-Methylated Quercetins, Highly Potent β-Secretase Inhibitors Isolated from Caragana Balchaschensis (Kom.) Pojark. Journal of Ethnopharmacology, 2021, 272, 113935. https://doi.org/10.1016/j.jep.2021.113935.
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Ban, Y. J.; Song, Y. H.; Kim, J. Y.; Cha, J. Y.; Ali, I.; Baiseitova, A.; Shah, A. B.; Kim, W.-Y.; Park, K. H. A Significant Change in Free Amino Acids of Soybean (Glycine Max L. Merr) through Ethylene Application. Molecules, 2021, 26 (4), 1128. https://doi.org/10.3390/molecules26041128.
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Kim, J. H.; Jang, D. H.; Lee, K. W.; Kim, K. D.; Shah, A. B.; Zhumanova, K.; Park, K. H. Tyrosinase Inhibition and Kinetic Details of Puerol A Having But-2-Enolide Structure from Amorpha Fruticosa. Molecules, 2020, 25 (10), 2344. https://doi.org/10.3390/molecules25102344.
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Zahoor, M.; Shah, A. B.; Naz, S.; Ullah, R.; Bari, A.; Mahmood, H. M. Isolation of Quercetin from Rubus Fruticosus, Their Concentration through NF/RO Membranes, and Recovery through Carbon Nanocomposite. A Pilot Plant Study. BioMed Research International, 2020, 2020, 1–7. https://doi.org/10.1155/2020/8216435.
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Bilal, H.; Ali, I.; Uddin, S.; Khan, I.; Said, A.; Rahman, M. U.; Khan, A. M.; Shah, A. B.; Ali, A. Biological Evaluation of Antimicrobial Activity of Calotropis Procera against a Range of Bacteria. Journal of Pharmacognosy and Phytochemistry, 2020, 9.
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Uddin, S., Ali, I., Hassan, M., Hamayun, L., Ali, U., Saud, S., Khan, I., Ahmad, W., Shah, A.B., Zeb, A., Khan, A.A., Therapeutic Applications of Coconut Water Mitigates Diabetes Mellitus in Oryctolagus Cuniculus (Rabbit). Biomedical Journal of Scientific & Technical Research, 2019, 16 (4). https://doi.org/10.26717/BJSTR.2019.16.002884.
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Khayam, S. M. U.; Zahoor, M.; Shah, A. B. Biological and Phytochemical Evaluation of Cotoneaster Microphyllus, Ficus Auriculata and Calotropis Procera. Latin American Journal of Pharmacy, 2019, 9.
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Zahoor, M.; Shah, A. B.; Gul, S.; Amin, S. HPLC-UV Analysis of Antioxidants in Citrus Sinensis Stem and Root Extracts. Journal of the Chemical Society of Pakistan, 2018, 40(3):595-601.
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Zafar, R.; Chishti, K. A.; Zahoor, M.; Shah, A. B. Screening/Assessment of Potential Drug-Drug Interactions in Neurology Ward of a Tertiary Care Hospital, Peshawar Khyber Pakhtunkhwa: Prevalence, Types and their Predictors. Pharmacologyonline, 2018.
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Zafar, R.; Zahoor, M.; Shah, A. B.; Majid, F. Determination of Antioxidants and Antibacterial Activities, Total Phenolic, Polyphenol and Pigment Contents in Nasturtium Officinale. Pharmacologyonline, 2017.
Interests
OUT OF OFFICE
Travel
Photography
Reading